Found 38 results
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Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD et al..  2015.  Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.. Am J Physiol Lung Cell Mol Physiol. 308(2):L208-20.
Wang L, Bittman R, Garcia JGN, Dudek SM.  2015.  Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate.. Microvasc Res. 99:102-9.
Sun X, Elangovan VRamamoorth, Mapes B, Camp SM, Sammani S, Saadat L, Ceco E, Ma S-F, Flores C, MacDougall MS et al..  2014.  The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants.. Am J Respir Cell Mol Biol. 51(5):660-7.
Usatyuk PV, Burns M, Mohan V, Pendyala S, He D, Ebenezer DL, Harijith A, Fu P, Huang LShuang, Bear JE et al..  2013.  Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction.. PLoS One. 8(5):e63007.
Ephstein Y, Singleton PA, Chen W, Wang L, Salgia R, Kanteti P, Dudek SM, Garcia JGN, Jacobson JR.  2013.  Critical role of S1PR1 and integrin β4 in HGF/c-Met-mediated increases in vascular integrity.. J Biol Chem. 288(4):2191-200.
Adyshev DM, Dudek SM, Moldobaeva N, Kim K-mi, Ma S-F, Kasa A, Garcia JGN, Verin AD.  2013.  Ezrin/radixin/moesin proteins differentially regulate endothelial hyperpermeability after thrombin.. Am J Physiol Lung Cell Mol Physiol. 305(3):L240-55.
Wang L, Chiang ET, Simmons JT, Garcia JGN, Dudek SM.  2011.  FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl.. Eur Respir J. 38(1):78-88.
Wolfson RK, Chiang ET, Garcia JGN.  2011.  HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption.. Microvasc Res. 81(2):189-97.
Berdyshev EV, Gorshkova I, Usatyuk P, Kalari S, Zhao Y, Pyne NJ, Pyne S, Sabbadini RA, Garcia JGN, Natarajan V.  2011.  Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase.. PLoS One. 6(1):e16571.
Mirzapoiazova T, Moitra J, Moreno-Vinasco L, Sammani S, Turner JR, Chiang ET, Evenoski C, Wang T, Singleton PA, Huang Y et al..  2011.  Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury.. Am J Respir Cell Mol Biol. 44(1):40-52.
Pendyala S, Moitra J, Kalari S, Kleeberger SR, Zhao Y, Reddy SP, Garcia JGN, Natarajan V.  2011.  Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter.. Free Radic Biol Med. 50(12):1749-59.
Usatyuk PV, He D, Bindokas V, Gorshkova IA, Berdyshev EV, Garcia JGN, Natarajan V.  2011.  Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways.. Am J Physiol Lung Cell Mol Physiol. 300(6):L840-50.
Zhao Y, Gorshkova IA, Berdyshev E, He D, Fu P, Ma W, Su Y, Usatyuk PV, Pendyala S, Oskouian B et al..  2011.  Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression.. Am J Respir Cell Mol Biol. 45(2):426-35.
Singleton PA, Mirzapoiazova T, Guo Y, Sammani S, Mambetsariev N, Lennon FE, Moreno-Vinasco L, Garcia JGN.  2010.  High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness.. Am J Physiol Lung Cell Mol Physiol. 299(5):L639-51.
Singleton PA, Chatchavalvanich S, Fu P, Xing J, Birukova AA, Fortune JA, Klibanov AM, Garcia JGN, Birukov KG.  2009.  Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.. Circ Res. 104(8):978-86.
Liu P, Li H, Cepeda J, Zhang LQin, Cui X, Garcia JGN, Ye SQing.  2009.  Critical role of PBEF expression in pulmonary cell inflammation and permeability.. Cell Biol Int. 33(1):19-30.
Singleton PA, Pendyala S, Gorshkova IA, Mambetsariev N, Moitra J, Garcia JGN, Natarajan V.  2009.  Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium.. J Biol Chem. 284(50):34964-75.
Sun X, Shikata Y, Wang L, Ohmori K, Watanabe N, Wada J, Shikata K, Birukov KG, Makino H, Jacobson JR et al..  2009.  Enhanced interaction between focal adhesion and adherens junction proteins: involvement in sphingosine 1-phosphate-induced endothelial barrier enhancement.. Microvasc Res. 77(3):304-13.
Berdyshev EV, Gorshkova I, Skobeleva A, Bittman R, Lu X, Dudek SM, Mirzapoiazova T, Garcia JGN, Natarajan V.  2009.  FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.. J Biol Chem. 284(9):5467-77.
Usatyuk PV, Gorshkova IA, He D, Zhao Y, Kalari SK, Garcia JGN, Natarajan V.  2009.  Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells.. J Biol Chem. 284(22):15339-52.
Zhao Y, Usatyuk PV, Gorshkova IA, He D, Wang T, Moreno-Vinasco L, Geyh AS, Breysse PN, Samet JM, Spannhake EWm et al..  2009.  Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells.. Am J Respir Cell Mol Biol. 40(1):19-30.
Chen W, Pendyala S, Natarajan V, Garcia JGN, Jacobson JR.  2008.  Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition.. Am J Physiol Lung Cell Mol Physiol. 295(4):L575-83.
Damico RL, Chesley A, Johnston L, Bind EP, Amaro E, Nijmeh J, Karakas B, Welsh L, Pearse DB, Garcia JGN et al..  2008.  Macrophage migration inhibitory factor governs endothelial cell sensitivity to LPS-induced apoptosis.. Am J Respir Cell Mol Biol. 39(1):77-85.
Gorshkova I, He D, Berdyshev E, Usatuyk P, Burns M, Kalari S, Zhao Y, Pendyala S, Garcia JGN, Pyne NJ et al..  2008.  Protein kinase C-epsilon regulates sphingosine 1-phosphate-mediated migration of human lung endothelial cells through activation of phospholipase D2, protein kinase C-zeta, and Rac1.. J Biol Chem. 283(17):11794-806.
Singleton PA, Moreno-Vinasco L, Sammani S, Wanderling SL, Moss J, Garcia JGN.  2007.  Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.. Am J Respir Cell Mol Biol. 37(2):222-31.